High Testosterone But Low Sex Drive? Check Your Prolactin

High Testosterone But Low Sex Drive? Check Your Prolactin

Increased testosterone levels from hormone replacement therapy are expected to bring on a ravenous sex drive in men. However some men either realize a short term increase in desire when testosterone replacement therapy is initiated and then is trails off, or it never comes on like expected. What gives? High testosterone levels are supposed to make your women run and hide! Believe it or not, prolactin is a hormone that causes pregnant women to produce breast milk! I know, seems kind of backwards, right? But, a high prolactin level (in men) is probably what is suppressing your libido. Abnormally high levels blunt the actions of dopamine, which is what primarily regulates your sex drive.
Prolactin, also known as lactogenic hormone, is produced by the pituitary gland.

 

Prolactin plays an important role in the reproductive health of both women and men. In women, prolactin acts to trigger lactation (the production of milk) after childbirth. In men, however, the specific function of prolactin is not well known. Although, in both men and women, prolactin levels seem to indicate a measure of sexual satisfaction. Prolactin is what tells your body that it’s satisfied after sex, and lets the arousal mechanism (dopamine) know it can settle down and get ready for round two.

 

 

As far as sex drive in men goes, high prolactin levels inhibit the release of gonadotropin-releasing hormone, which in turn causes a decrease in luteinizing hormone, which leads to reduced follicle stimulating hormone, which leads to decreased testosterone production. These decreases cause a reduction of sperm production, impaired sperm motility, and poor sperm quality. The overt physical symptoms of such an impaired hormone cascade such as gynecomastia, erectile dysfunction and lost libido, may not appear until prolactin has been elevated for an extended period of time.

 

Unfortunately, no one agrees on what the optimal prolactin level is for men, although a blood test could tell if it has significantly increased. A typical prolactin level may range from 2-18 mcg/L but a high prolactin level might be 10-20 times the reference range. There are some normal fluctuations in prolactin. Your prolactin levels change throughout the day, so the blood test is usually given, like most blood tests, first thing in the morning - about three hours after you wake—to establish a consistent reference range.

 

If your prolactin level is very high (hyperprolactemia), it’s time to look for the cause. A level of 200 mcg/L, more or less, would usually prompt a clinician to do an MRI to look for a prolactinoma, a tumor in the pituitary gland that actually secretes excess prolactin. Other pituitary problems, or tumors in its vicinity, may cause an unusually high prolactin level. Your doctor may also look at other medications you may be taking to look for an adverse interaction; certain medications can raise the level of prolactin. Examples include antidepressants, proton pump inhibitors, select blood pressure medications, and several anti-psychotics. Cocaine use can also raise prolactin.

 

You might also have a high prolactin level if you have kidney disease, an under active thyroid, or a disorder involving the thalamus—the area in your brain that controls the pituitary gland—or hypothalamic disease. Obviously, treatment for hyperprolactemia depends on the cause. Medication-related causes may be solved simply with an adjustment by your doctor. For tumors, the treatments generally target shrinking the tumor and limiting its secretion with drug therapy (dopamine or dopamine agonists).

 

Drugs that dampen prolactin production and its release, such as bromocriptine, cabergonline and HCG can lower serum prolactin levels enough to restore male fertility and libido. In any case, men with reduced libido, with a concomitant a high testosterone level, can put the lead back in their pencil once prolactin levels are brought back down.
April 21, 2017 by Richard Rodriguez

Dinitrophenol Side Effects: Why Use With Caution

Dinitrophenol Side Effects: Why Use With Caution

 

Dinitrophenol (DNP) has serious side effects. It's something that needs to be used with caution. Everyone wants to lose body fat. Getting lean and shredded is what every guy and girl in the gym wants to do -  get more, more, more and more ripped.....  But, apparently, such a quest is not so easily achieved as evinced by the paucity of people running around with deeply etched abs and striated shredded muscle. You just don't see a lot of them. If fat was so easy to lose, then why isn't the beach packed with killer ripped bodies? The shores usually look littered with bloated aquatic mammal carcasses rather than anything lean and athletic. 

 

While the path to ripped abs is littered with difficulty, false starts and failure, numerous shortcuts to losing body fat have come and gone.  Some of them, one in particular, had proven to be very effective. Unfortunately, its not very good for you. In fact, while dinitrophenol side effects of DNP are few, they can be quite bad, so dinitrophenol must be used with caution.  To understand why, you might want to consider that DNP, or 2,4-dinitrophenol is a poisonous industrial chemical, just a couple of molecules away  from nitroglycerine, used in the manufacture of  herbicides and antiseptics.  As you can see, we're not dealing with an herbal supplement here. Dinitrophenol is at the very least harsh, yet it has an incredible ability to burn fat. 

 

In 1933, an American researcher discovered that  DNP dramatically speeds up the metabolism leading to rapid weight loss in human subjects. In the 1930s dinitrophenol was used extensively as a dieting aid. Some 100,000 people used DNP (in pill form) during its first year on the market. Typical weight loss averaged a respectable 3.3 pounds per week. The important thing that should be noted is that this weight loss occurred without dietary restrictions; users lost body fat even though they ate whatever they wanted.

 

DNP works as an uncoupling agent. It affects the conversion of ATP to ADP in the Kreb cycle. Normally, the Kreb cycle facilitates energy production from glucose when ATP is converted to ADP. Dinitrophenol  “uncouples” this reaction and instead of producing energy when ATP is converted to ADP, the energy is instead given off as heat. Think of it as a hole poked in a gas tank.  Unchecked, this heat can increase body temperature to a fatal degree.

 

While DNP side effects usually include profuse sweating, dehydration, nausea, vomiting, restlessness, headaches, rapid breathing and a rapid or irregular heartbeat, these side effects are fungible nuisances compared to it's main side effect, death. The elevation in body temperature can rise to a level where the nervous system short circuits and you can go into cardiac arrest and die. You basically cook yourself to death.

 

Now, this is not to say that you will die if you use DNP, many people have used it and lost lots of body fat and didn't die. They did, however, have a hard time training. Look at ti this way, if DNP uncouples the the link in the metabolic pathway which converts ATP to ADP to produce energy, and instead gives off that energy as heat, from where will your energy come to train? Dinitrophenol users report serious difficulty in manufacturing training intensity while using the chemical.

 

So, not only do dinitrophenol side effects warrant its use with caution, you'll also need to be aware of how it affects your energy levels.

April 19, 2017 by Richard Rodriguez

Testosterone Replacement Therapy

 

 

Testosterone is a hormone produced by the testicles and is responsible for the correct development of male sexy characteristics.This natural decline begins after age 30 and extends throughout life. As a man ages, the allowance of testosterone in his body step-by-step turns down.Testosterone is furthermore important for sustaining sinew bulk, ample grades of red blood units, skeletal part development, a sense of well-being, and sexy function. Inadequate output of testosterone is not a widespread cause of erectile dysfunction; although, when ED does occur due to decreased testosterone production, testosterone replacement treatment may improve the problem.

What Causes Testosterone Deficiency?

As a man ages, the amount of testosterone in his body step-by-step turns down. This natural down turn starts after age 30 and extends all through life. The implication of this down turn is controversial and badly appreciated. Among other potential determinants of testosterone deficiency are:

  • Injury or infection to the testicles
  • Chemotherapy or emission remedy for cancerous disease
  • Hemochromatosis (too much iron in the body)
  • Dysfunction of the pituitary gland (a gland in the mind that makes many significant hormones)
  • Medications, including hormone analogues utilized to heal prostate cancerous disease and steroids
  • Chronic illness
  • Cirrhosis of the liver
  • Chronic renal (kidney) malfunction
  • AIDS
  • Inflammatory infection such as sarcoidosis (a status that determinants inflammation of the lungs and other organs)
  • Tension
  • Alcoholism
  • Congenital conditions, Kallman’s Syndrome (low hormones, inability to stink and other abnormalities)

What Are The Alterations That Happen In The Body With Testosterone Deficiency?

Alterations that occur with testosterone deficiency include:

  • A decrease in sinew mass, with a boost in body fat
  • Variable consequences on cholesterol metabolism
  • A decline in hemoglobin and possibly gentle anemia
  • Fragile skeletal parts (osteoporosis)
  • A decline in body hair
How Do I Find Out If I Have Reduced Testosterone?

The only unquestionable way to notice the condition is to have your doctor measure the allowance of testosterone in your blood. Because testosterone levels fluctuate all through the day, several measurements will need to be taken to notice a deficiency. medical practitioners prefer, if likely, to check levels early in the forenoon since this is when testosterone grades are at their highest.

What Choices Are Accessible For Testosterone Replacement Therapy?

The choices accessible for testosterone replacement are: Intramuscular injections, usually every two or three weeks

Testosterone patches damaged either on the body or on the scrotum (the sac that contains the testicles). These patches are utilized daily. The body patch submission is rotated between the buttocks, arms, back or abdomen etc.

Testosterone gels that are directed everyday to the bears, top arms, or abdomen.

Each of these choices supplies ample levels of hormone replacement. Each has edge consequences and benefits and handicaps. Intramuscular injections produce wider swings in hormone concentration, with higher grades soon after the injection and smaller levels just before the next injection is due. They may furthermore produce rises in body-fluid cell count that are higher than normal.

The body patches may make skin irritation in an important number of men, needing discontinuation of the patch. The gels need care in making sure that the hormone is not accidentally transferred to another individual or colleague.

There are currently no tablets accessible in the joined States that supply adequate grades of hormone replacement. In supplement, oral medications may produce liver abnormalities and are to be bypassed.

The alternative of hormone replacement treatment is best made with a methodical consideration between a patient and his physician.

April 19, 2017 by Richard Rodriguez